{"id":290,"date":"2018-01-17T18:54:12","date_gmt":"2018-01-17T18:54:12","guid":{"rendered":"https:\/\/aurelis.org\/blog\/?p=290"},"modified":"2018-05-05T19:13:57","modified_gmt":"2018-05-05T19:13:57","slug":"7-eye-opener-double-blind-studies","status":"publish","type":"post","link":"https:\/\/aurelis.org\/blog\/healthcare\/7-eye-opener-double-blind-studies","title":{"rendered":"7. An eye-opener on double-blind studies"},"content":{"rendered":"<p style=\"text-align: center;\">The core of present-day scientific medicine is more and more boiling down to \u2018evidence based medicine\u2019 (EBM). The essence of EBM is double-blind studies: comparing a new supposedly-active substance to placebo whereby both prescriber(s) and patients are ignorant (\u2018blind\u2019) in regard to whether they get placebo or the \u2018active\u2019 substance.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">Nice.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">Everything (really: everything in this matter) stands or falls with whether blind is blind. If it is, then so much the better. If it isn\u2019t, then present-day scientific medicine is still at a low level of science and should evolve from this with extreme urgency.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">So: is blind very blind? I don\u2019t think so.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">The point is that a placebo doesn\u2019t work through <em>conscious<\/em> expectation. As a matter of fact, it doesn\u2019t work through a conscious whatsoever. If a placebo for instance lowers the blood pressure, it\u2019s not because you consciously lower your BP. Purely consciously, you\u2019re not capable of doing so. Placebo (or better said: your own inner strength in this) works through the <em>sub<\/em>conscious. Therefore the <em>sub<\/em>conscious is what is important in all this.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">So the pertinent question is not whether you are consciously blind, but rather whether you are <em>sub<\/em>consciously blind. That is a question that has hardly at all entered into scientifically.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">Take the side effects of medication. Does the subconscious register consciously-felt side effects? To me there is no doubt about this. Can it also register not-consciously-felt side effects? Let me ask it like this: why shouldn\u2019t it? One can be certain that the subconscious registers <em>any<\/em> bodily change. Therefore also the slightest side-effect of medication.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">Since medication (the \u2018active substance\u2019 in double-blind studies) always has lots of side effects, while a pure placebo has as good as none, to the subconscious at least the difference is always clear. This is: at this very important level, there is little or no double-blindness at all. Let me repeat this.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">There is little or no double-blindness at all!<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">The same argument can be made not only for the side-effects, but also for the meant effect. This makes it even worse!<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">Conclusion: a double-blind study compares an active substance, potentially having lots of placebo-activity, to a placebo with relatively little placebo-activity. While such a study is supposed to lead to a subtraction of placebo-activity, quite the reverse happens in reality. Scientists are beginning to become aware of this problem. All too slowly.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">As said, this is the essence of the core of present-day scientific medicine.<\/p>\n<p style=\"text-align: center;\">\u25ca\u25ca\u25ca<\/p>\n<p style=\"text-align: center;\">\n<div data-object_id=\"290\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_no_cat cbxwpbkmarkwrap-post \"><a  data-redirect-url=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/290\"  data-display-label=\"0\" data-show-count=\"0\" data-bookmark-label=\" \"  data-bookmarked-label=\" \"  data-loggedin=\"0\" data-type=\"post\" data-object_id=\"290\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\"  style=\"display:none;\" > <\/span><\/a> <div  data-type=\"post\" data-object_id=\"290\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-290\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3>\n\t\t<form name=\"loginform\" id=\"loginform\" action=\"https:\/\/aurelis.org\/blog\/wp-login.php\" method=\"post\">\n\t\t\t\n\t\t\t<p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Username or Email Address<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t<p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Password<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t\t<p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Remember Me<\/label><\/p>\n\t\t\t<p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Log In\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/290\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t<\/form><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>The core of present-day scientific medicine is more and more boiling down to \u2018evidence based medicine\u2019 (EBM). The essence of EBM is double-blind studies: comparing a new supposedly-active substance to placebo whereby both prescriber(s) and patients are ignorant (\u2018blind\u2019) in regard to whether they get placebo or the \u2018active\u2019 substance. \u25ca\u25ca\u25ca Nice. \u25ca\u25ca\u25ca Everything (really: <a class=\"moretag\" href=\"https:\/\/aurelis.org\/blog\/healthcare\/7-eye-opener-double-blind-studies\">Read the full article&#8230;<\/a><\/p>\n<div data-object_id=\"290\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_no_cat cbxwpbkmarkwrap-post \"><a  data-redirect-url=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/290\"  data-display-label=\"0\" data-show-count=\"0\" data-bookmark-label=\" \"  data-bookmarked-label=\" \"  data-loggedin=\"0\" data-type=\"post\" data-object_id=\"290\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\"  style=\"display:none;\" > <\/span><\/a> <div  data-type=\"post\" data-object_id=\"290\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-290\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3>\n\t\t<form name=\"loginform\" id=\"loginform\" action=\"https:\/\/aurelis.org\/blog\/wp-login.php\" method=\"post\">\n\t\t\t\n\t\t\t<p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Username or Email Address<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t<p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Password<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t\t<p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Remember Me<\/label><\/p>\n\t\t\t<p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Log In\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/290\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t<\/form><\/div><\/div><\/div>","protected":false},"author":2,"featured_media":291,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":""},"categories":[11,13],"tags":[],"jetpack_featured_media_url":"https:\/\/i1.wp.com\/aurelis.org\/blog\/wp-content\/uploads\/2018\/02\/Sticky7.jpg?fit=964%2C561&ssl=1","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9Fdiq-4G","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/290"}],"collection":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/comments?post=290"}],"version-history":[{"count":1,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/290\/revisions"}],"predecessor-version":[{"id":292,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/290\/revisions\/292"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/media\/291"}],"wp:attachment":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/media?parent=290"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/categories?post=290"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/tags?post=290"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}