{"id":14123,"date":"2024-01-13T16:10:32","date_gmt":"2024-01-13T16:10:32","guid":{"rendered":"https:\/\/aurelis.org\/blog\/?p=14123"},"modified":"2024-02-09T09:01:54","modified_gmt":"2024-02-09T09:01:54","slug":"the-mind-in-pnie","status":"publish","type":"post","link":"https:\/\/aurelis.org\/blog\/healthcare\/the-mind-in-pnie","title":{"rendered":"The Mind in PNIE"},"content":{"rendered":"\n<h3><em>Over the years, the role of the mind in Psycho-Neuro-Immuno-Endocrinology (PNIE) has become increasingly apparent. This trend is bound to continue, and Lisa is bound to play a significant role in this evolution.<\/em><\/h3>\n\n\n\n<blockquote class=\"wp-block-quote\"><p>PNIE shows the intricate connections between different systems in the human being as a whole. Regarding the mind (psyche), one can go a step further. This is not a \u2018different system\u2019 but rather the result of a specific view of the whole. There are no particular mind-molecules, mind-cells, or mind-substances.<\/p><\/blockquote>\n\n\n\n<blockquote class=\"wp-block-quote\"><p>You find some <a href=\"https:\/\/aurelis.org\/blog\/category\/immune-related\">immune related blogs here<\/a>.<\/p><\/blockquote>\n\n\n\n<p><strong>Another trend: complexity of the physical systems<\/strong><\/p>\n\n\n\n<p>The more that researchers unravel each system of the human body at the cellular and molecular level, the more complexity is found at each level and between systems and levels \u2015 as if nature has never been happy with simple solutions.<\/p>\n\n\n\n<p>There is good reason for this. Complexity brings additional possibilities as well as robustness. With the right \u2018energy,\u2019 a complex system is self-uplifting and even self-healing through positive and negative feedback loops. Natural evolution is one example, as is much of what happens within each natural organism.<\/p>\n\n\n\n<p>On the other hand, it also brings a vulnerability: the propensity for self-enhancing chaos. Within or near this chaos, a structure can emerge that distracts a lot of the chaos&#8217; energy \u2015 thus forming a \u2018dissipative structure.\u2019 To make this clear with a frequently used example, think of a river that streams harder over a specific stretch, thus concentrating a lot of energy. This makes the water molecules behave near-chaotically. If circumstances collide, this turns into a whirlpool \u2015 an example of a dissipative structure. It dissipates the molecules and the energy into a new entity and a dangerous one for that.<\/p>\n\n\n\n<p>We&#8217;ll come back to this in a minute.<\/p>\n\n\n\n<p><strong>The mind and complexity<\/strong><\/p>\n\n\n\n<p>We don\u2019t see \u2018mind\u2019 in simple systems. By intuition, we also know that it\u2019s not possible to see it there. \u2018Mind\u2019 seems to need a complex substrate.<\/p>\n\n\n\n<p>So far, so good. But there\u2019s another way to look at this. What we call \u2018mind\u2019 may be the result of <em>any<\/em> super-complex system. Then, it\u2019s just a term we use to denote what we cannot comprehend in another way. Note that \u2018super-complex\u2019 should be taken literally as more than just \u2018complex.\u2019 We see complex systems in much of nature but in nothing as super-complex as ourselves. Therefore, for a long time, people have seen &#8216;mind&#8217; as almost a synonym of &#8216;human mind.&#8217;<\/p>\n\n\n\n<p><strong>This is then also the reason why \u2018mind\u2019 seems mysterious.<\/strong><\/p>\n\n\n\n<p>If there is nothing about some entity beyond our reach of comprehension, then we are not keen to see it as possessing \u2018mind\u2019 or even being \u2018intelligent\u2019 in the first place. Thus, the mystery comes <em>before<\/em> the mind.<\/p>\n\n\n\n<p>For instance, people used to see the possibility of making mathematical calculations as a hallmark of intelligence. Not so long ago, \u2018computers\u2019 were intelligent people who made many demanding calculations in mainly the business world. When \u2013 comprehensible \u2013 machines started doing the job, the job itself lost its aura of intelligence. Calculating devices are not particularly seen as intelligent nowadays. Mystery gone \u2015 intelligence gone \u2015 mind gone.<\/p>\n\n\n\n<p><strong>Eventually, \u2018mind\u2019 is complexity itself, also in PNIE.<\/strong><\/p>\n\n\n\n<p>Thus, in simple terms, we come to the basis of <a href=\"https:\/\/aurelis.org\/blog?p=4552\">mind-body unity<\/a>. \u2018Body\u2019 and \u2018mind\u2019 are two ways of looking at the same thing.<\/p>\n\n\n\n<p>In PNIE, complexity abounds in each physical system: the neurological, the immunological, and the endocrinological. This also shows again what we already know well: the mind is not confined to the working of the brain. Included is the complexity of the whole body. We think with every letter of PNIE, at least.<\/p>\n\n\n\n<p>Undoubtedly, we are far from reaching the end of related discoveries. Future research will show a lot more complexity. Otherwise said, it will show a lot more \u2018mind.\u2019<\/p>\n\n\n\n<p>Are you following me?<\/p>\n\n\n\n<p><strong>We are still talking about the same \u2018mind\u2019 \u2015 no magic.<\/strong><\/p>\n\n\n\n<p>Probably the most important consequence is that we need to take the mind much more seriously in all diseases that are now seen as physically very complex.<\/p>\n\n\n\n<p>One example is the large group of (auto-)immune-mediated inflammatory diseases, comprising psoriasis, <a href=\"https:\/\/aurelis.org\/blog?p=14039\">multiple sclerosis<\/a>, ulcerative colitis, Crohn\u2019s disease, <a href=\"https:\/\/aurelis.org\/blog?p=5440\">rheumatic arthritis<\/a>, systemic lupus, and many more. [1] Each of these disorders can be seen as a dissipative structure within the super-complexity that we call \u2018human being\u2019 \u2015 basically analogous to a river\u2019s whirlpool, only in a much more complex environment and in which apparently quite a few things can go wrong.<\/p>\n\n\n\n<p>We can and should try to manage\/treat these conditions as well as possible from a physical perspective. Besides that, we should also never forget the mind perspective, not by reducing it but by taking into account the inherent \u2013 by definition \u2013 degree of complexity. Only by valuing both can we lend optimal services to many patients.<\/p>\n\n\n\n<p><strong>But how?<\/strong><\/p>\n\n\n\n<p>That\u2019s where <a href=\"https:\/\/aurelis.org\/blog?p=10620\">Lisa<\/a> comes to the rescue, using A.I. to take into account, as said, the true complexity of the human mind.<\/p>\n\n\n\n<p>In my view, this will also lead us to a better understanding of who we are and why it matters.<\/p>\n\n\n\n<p>\u2015<\/p>\n\n\n\n<p>[1] <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36101354\/\" target=\"_blank\" rel=\"noreferrer noopener\">Ortega MA, Garc\u00eda-Montero C, Fraile-Martinez O, Alvarez-Mon MA, G\u00f3mez-Lahoz AM, Lahera G, Monserrat J, Rodriguez-Jimenez R, Quintero J, \u00c1lvarez-Mon M. Immune-Mediated Diseases from the Point of View of Psychoneuroimmunoendocrinology. Biology (Basel). 2022 Jun 28;11(7):973. doi: 10.3390\/biology11070973. PMID: 36101354; PMCID: PMC9312038.<\/a><\/p>\n<div data-object_id=\"14123\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_no_cat cbxwpbkmarkwrap-post \"><a  data-redirect-url=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/14123\"  data-display-label=\"0\" data-show-count=\"0\" data-bookmark-label=\" \"  data-bookmarked-label=\" \"  data-loggedin=\"0\" data-type=\"post\" data-object_id=\"14123\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\"  style=\"display:none;\" > <\/span><\/a> <div  data-type=\"post\" data-object_id=\"14123\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-14123\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3>\n\t\t<form name=\"loginform\" id=\"loginform\" action=\"https:\/\/aurelis.org\/blog\/wp-login.php\" method=\"post\">\n\t\t\t\n\t\t\t<p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Username or Email Address<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t<p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Password<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t\t<p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Remember Me<\/label><\/p>\n\t\t\t<p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Log In\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/14123\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t<\/form><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Over the years, the role of the mind in Psycho-Neuro-Immuno-Endocrinology (PNIE) has become increasingly apparent. This trend is bound to continue, and Lisa is bound to play a significant role in this evolution. PNIE shows the intricate connections between different systems in the human being as a whole. Regarding the mind (psyche), one can go <a class=\"moretag\" href=\"https:\/\/aurelis.org\/blog\/healthcare\/the-mind-in-pnie\">Read the full article&#8230;<\/a><\/p>\n<div data-object_id=\"14123\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_no_cat cbxwpbkmarkwrap-post \"><a  data-redirect-url=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/14123\"  data-display-label=\"0\" data-show-count=\"0\" data-bookmark-label=\" \"  data-bookmarked-label=\" \"  data-loggedin=\"0\" data-type=\"post\" data-object_id=\"14123\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\"  style=\"display:none;\" > <\/span><\/a> <div  data-type=\"post\" data-object_id=\"14123\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-14123\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3>\n\t\t<form name=\"loginform\" id=\"loginform\" action=\"https:\/\/aurelis.org\/blog\/wp-login.php\" method=\"post\">\n\t\t\t\n\t\t\t<p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Username or Email Address<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t<p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Password<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t\t<p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Remember Me<\/label><\/p>\n\t\t\t<p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Log In\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/14123\" \/>\n\t\t\t<\/p>\n\t\t\t\n\t\t<\/form><\/div><\/div><\/div>","protected":false},"author":2,"featured_media":14124,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":""},"categories":[11,81],"tags":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/aurelis.org\/blog\/wp-content\/uploads\/2024\/01\/2309.jpg?fit=960%2C560&ssl=1","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9Fdiq-3FN","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/14123"}],"collection":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/comments?post=14123"}],"version-history":[{"count":20,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/14123\/revisions"}],"predecessor-version":[{"id":14456,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/posts\/14123\/revisions\/14456"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/media\/14124"}],"wp:attachment":[{"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/media?parent=14123"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/categories?post=14123"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/aurelis.org\/blog\/wp-json\/wp\/v2\/tags?post=14123"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}